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CASE STUDY · PHARMA

WHO-GMP Cleanroom.6 Doorways. Audit-Ready.

A WHO-GMP certified pharmaceutical formulations unit in Baddi, Solan (HP) needed cleanroom-grade doorway separation for its tablet compression and packaging zones — ahead of a scheduled CDSCO audit. Chronovex supplied and installed 200mm × 2mm transparent PVC strip curtains at 6 critical doorways within 9 working days, fully compliant with WHO TRS 961 Annex 2.

WHO-GMP compliant
Baddi, Solan HP
Installed Jan 2025
CDSCO audit cleared
6 doorways
Separated
Compression, packing, QC, MR, storage
ISO 8
Particulate
Maintained class limits post-install
9 days
Lead time
Survey to CDSCO sign-off
0
Audit observations
On the strip curtain installation
THE BRIEF

When the CDSCO audit is 21 days away

A formulations contract manufacturer in Baddi pharma cluster needed urgent doorway separation between Grade D and Grade C zones to clear an upcoming CDSCO inspection on Schedule M compliance.

THE COMPLIANCE PROBLEM

21 days to CDSCO audit, 6 doorways without proper separation

The plant's QA head, Dr. Sharma, had received a pre-audit observation from the consultant: 6 doorways between Grade D (general manufacturing) and Grade C (tablet compression) zones had no physical separation. Risk: a formal Schedule M observation could delay product approvals by 60-90 days.

THE DIAGNOSIS

We mapped airflow, not just doorways

Our pharma vertical lead, Anita Singh (B.Pharm + 9 yrs cleanroom), spent a full shift mapping airflow at each doorway with a smoke pencil and digital anemometer. 4 doorways had reverse pressure during forklift movement — a direct cross-contamination risk under WHO TRS 961 Annex 2.

THE SOLUTION

200mm × 2mm flexible transparent PVC strip curtain with 67% overlap

We specified pharma-grade Chronovex PVC strip — 200mm wide, 2mm thick, transparent (visual continuity for forklift operators), with double-fold 67% overlap design. Mounting via SS-304 universal hooks. All strip joints heat-welded for crevice-free GMP compliance.

THE OUTCOME

CDSCO audit cleared with zero strip-curtain observations

21 days later, the CDSCO inspector examined all 6 doorways. Particulate count at the Grade C side stayed within ISO 8 limits during full forklift operation. Zero observations on the strip-curtain installation. The audit closed in 2 days with no major observations on facility design.

EQUIPMENT

Exactly what was installed

Full bill-of-materials with HSN codes, GST-billed and warranty-tracked.

Item
HSN
Qty
Warranty
Chronovex PVC Strip Curtain 200mm × 2mm transparent (pharma-grade)
39204900
60 metres
12 months
SS-304 universal mounting hooks
73262090
60 hooks
5 years
Heat-welded overlap joints (67% overlap)
-
Included
-
CDSCO documentation pack (TRS 961 alignment)
-
Provided
-
Anita's team understood Schedule M better than our consultant. They redesigned the overlap at our packing zone doorway and the CDSCO inspector specifically complimented that doorway in his closing remarks.
DS
Dr. S. Sharma
Head — QA, Formulations Unit, Baddi HP
FAQ

Frequently asked questions

Direct answers from our project engineers.

Is your PVC strip cleanroom-grade?+
Yes. We use 100% virgin PVC with stabilisers compliant with WHO TRS 961 Annex 2 and FDA 21 CFR 177.1950. Each consignment ships with a material composition certificate.
How often does the strip need replacement?+
Under cleanroom conditions (climate-controlled, no UV exposure), our PVC strip retains transparency for 18-24 months. We offer a 12-month free replacement clause if transparency degrades to >15% haze.
Do you supply for ISO 7 / Grade B zones?+
Yes. For ISO 7 / Grade B, we recommend our 300mm × 3mm anti-static variant. Our pharma vertical can walk you through the choice based on your QA matrix.
Is the install dust-free?+
We use a mobile HEPA-filtered vacuum and conduct install operations during plant shutdown or weekend windows. Particulate count is monitored continuously and signed off before equipment handover.

Pharma audit in the next 30 days?

Our pharma vertical can fast-track survey + supply + install within 9-14 working days for projects in Baddi, Vapi, Hyderabad, Goa and Sikkim industrial belts.

Book Pharma Audit Support